Regulation of Cell Membrane Permeability in Skeletal Muscle
نویسندگان
چکیده
منابع مشابه
Regulation of cell membrane permeability in skeletal muscle. I. Action of insulin and trypsin on the transport system for sugar.
The mechanism of the stimulatory action of insulin on the transport of sugar across the plasma membrane of skeletal muscle cells was studied by kinetic analysis of the penetration of 3-O-methyl-D-glucose into isolated frog sartorius muscles. As part of this evaluation, the effects of trypsin and insulin were compared. Phospholipase C exerted a much smaller effect on permeability than either of ...
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Unidirectional chloride effluxes from small bundles of muscle fibers were measured under equilibrium conditions. It was found that chloride effluxes are described by the constant field theory with a chloride permeability constant, P(cl), which is independent of the chloride concentration and the membrane potential. The value of P(cl) at neutral pH was found to be 5 x 10(-6) cm/sec. Chloride mov...
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Duchenne muscular dystrophy is a severe muscle wasting disease caused by a mutation in the gene for dystrophin--a cytoskeletal protein connecting the contractile machinery to a group of proteins in the cell membrane. At the end stage of the disease there is profound muscle weakness and atrophy. However, the early stage of the disease is characterised by increased membrane permeability which all...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1969
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)91732-1